Intravenous Lidocaine and Postoperative Cognition: Reply

Intraoperative intravenous lidocaine.

BACKGROUND AND OBJECTIVES Most patients undergoing surgery experience moderate to severe pain, indicating the need to improve the anesthetic technique. Intravenous lidocaine has been widely used in the treatment of chronic pain. The objective of this report was to review the use of intravenous lidocaine for postoperative analgesia. CONTENTS The pharmacologic aspects and mechanism of action of...

Meta-analysis of intravenous lidocaine and postoperative recovery after abdominal surgery.

BACKGROUND Continuous intravenous administration of lidocaine may decrease the duration of ileus and pain after abdominal surgery. METHODS Three databases (Medline, Embase and the Cochrane Controlled Trials Register) were searched to retrieve randomized controlled trials comparing continuous intravenous lidocaine infusion during and after abdominal surgery with placebo. Study design was score...

Perioperative intravenous lidocaine has preventive effects on postoperative pain and morphine consumption after major abdominal surgery.

UNLABELLED Sodium channel blockers are approved for IV administration in the treatment of neuropathic pain states. Preclinical studies have suggested antihyperalgesic effects on the peripheral and central nervous system. Our objective in this study was to determine the time course of the analgesic and antihyperalgesic mechanisms of perioperative lidocaine administration. Forty patients undergoi...

Perioperative Use of Intravenous Lidocaine.

Intravenous regional anesthesia using lidocaine and clonidine.

BACKGROUND Clonidine has been added to local anesthetic regimens for various peripheral nerve blocks, resulting in prolonged anesthesia and analgesia. The authors postulated that using clonidine as a component of intravenous regional anesthesia (IVRA) would enhance postoperative analgesia. METHODS Forty-five patients undergoing ambulatory hand surgery received IVRA with lidocaine, 0.5%, and w...